Urticaria causes itchy, raised welts (wheals) on the skin, often with a pale centre and surrounding redness, that typically come and go over hours — individual wheals usually resolve within 24 hours, though new ones can continue to appear elsewhere. It can affect any part of the body and is frequently accompanied by swelling of the deeper layers of skin, known as angioedema, which most often affects the lips, eyelids, or hands.
Treatment aims to control symptoms and is generally stepped up if the initial approach isn't enough:
Most people with chronic urticaria need an individualised, and sometimes long-term, treatment plan, since the condition can persist for months to years before settling.
Urticaria occurs when histamine and other chemicals are released from cells in the skin, causing the blood vessels to leak fluid into the surrounding tissue. What triggers this release varies:
In chronic urticaria, a specific cause often can't be identified even after investigation, which can be frustrating but doesn't mean the condition isn't real or treatable.